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Aspirin is one of the oldest and most intensively studied medications in human history. As a non-steroidal anti-inflammatory drug (NSAID), aspirin has historically been used to reduce fever and alleviate pain. With its now wide range of uses, it is no wonder aspirin and its affiliates are being coined “wonder drugs.”

Studies have found that there is a definite link between long-term aspirin use and lower rates of cancer. This connection is due to aspirin’s anti-inflammatory properties and its sensitivity to pH. When combined with diflunisal, another NSAID, this treatment works to induce pore-formation and apoptosis (programmed cell death) in cancer cells. This process effectively shrinks tumors and kills cancer with no adverse effects on healthy organs.

Both aspirin and diflunisal are derivatives of salicylic acid. Within the body, pH-sensitive salicylic acids attack acidic tumor cells without harming any healthy basic tissue. Because of this unique internal process, administering aspirin and diflunisal is a safe and well-tolerated treatment against cancer.

Administration of Aspirin Therapy

To maximize effectiveness, both aspirin and diflunisal are introduced to the body via IV infusion. Aspirin is injected as a pre-infusion, so the diflunisal has a stronger long-term benefit.

Injecting diflunisal alone in the bloodstream would result in the patient’s albumin proteins to saturate the medication, preventing it from having any therapeutic effect. When aspirin is injected first, the albumin proteins catch the aspirin molecules, allowing diflunisal to flow freely through tissues and destroy cancerous cells.

For patients in our German clinic, aspirin therapy is administered 4 days a week (Monday-Thursday) for 3 weeks. For compromised patients or patients too sick to travel, we offer this treatment as an internationally-delivered service. Unifontis nurses will travel directly to your doorstep for both infusion therapy and personalized vaccine delivery.

History of Aspirin Therapy

1550 BC, the ancient Egyptians used willow as a pain reliever and fever reducer due to its salicylic acid properties. They even recorded willow’s therapeutic benefits in the Ebers Papyrus, a classical medical text full of herbal knowledge. Willow continued to be administered as a tea through 400 BC by the Greek Hippocrates for pain relief during childbirth.

In the 19th century, the active ingredient in willow was successfully extracted by Johann Büchner, a professor of pharmacy at Munich University, Germany. Eventually, this extract was combined with other compounds to generate what we now know as aspirin.

Aspirin soon became the most frequently-sold painkiller on the market, and researchers began exploring the drug’s multifunctionality. This soon led to the discovery that aspirin aided in cancer prevention and helped destroy cancerous cells!

Studies of Aspirin Therapy

Willecke-Hochmuth, Regina et al., “Treatment of advanced solid tumours with NSAIDs: Correlation of quantitative monitoring of circulating tumour cells and positron emission tomography-computed tomography imaging.” Oncology letters vol. 12,3 (2016): 1711-1716. doi:10.3892/ol.2016.4878

Rayburn, Elizabeth R et al., “Anti-Inflammatory Agents for Cancer Therapy.” Molecular and cellular pharmacology vol. 1,1 (2009): 29-43. doi:10.4255/mcpharmacol.09.05

Holmes, Michelle D et al., “Aspirin intake and survival after breast cancer.” Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 28,9 (2010): 1467-72. doi:10.1200/JCO.2009.22.7918Hawk, E T, and J L Viner. “Aspirin: still learning about the wonder drug.” Gut vol. 52,11 (2003): 1535-6. doi:10.1136/gut.52.11.1535

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